Combined medication for intravaginal use. It has antimicrobial, and antifungal activity protivoprotozoynoe. Omnadren 250 results relates to 5-nitro-imidazoles.Restores Omnadren 250 results intracellular transport proteins of anaerobic microorganisms and protozoa, which interacts with DNA microbial cells by inhibiting synthesis of nucleic acids, which leads to the death of microorganisms.
It is an effective antimicrobial and antiprotozoal agent broad spectrum. It is active against Trichomonas vaginalis, Giardia intestinalis, Entamoeba histolytica , Lamblia intestinalis, as well as against obligate anaerobes (sporo- and asporogenous) – Bacteroides spp. (B. fragilis, B. ovatus, B. distasonis, B. thetaiotaomicron, B. vulgatus), Fusobacterium spp., Clostridium spp., Peptostreptococcus spp., Eubacterium sensitive strains. He susceptible aerobic microorganisms and facultative anaerobes.
When subjected intravaginal application of Omnadren 250 results systemic absorption. The maximum concentration in blood is about 50% of the maximum concentration which is reached after a single dose equivalent dose Omnadren 250 results inside. Almost completely metabolized in the liver to form inactive derivatives.
The half-life of 8 hours. Write mainly in the urine.
- bacterial vaginitis
- Trichomonas vaginitis
- fungal vaginitis
- vaginitis caused by mixed flora Prevention
- before the surgical treatment of gynecological diseases
- before birth and abortion
- before and after intrauterine konratseptivnyh funds
- before and after the coagulation of the cervix
- before hysterographyContraindications
: Hypersensitivity to the drug; blood diseases; incoordination, organic CNS (including epilepsy); hepatic insufficiency (in the case of the appointment of large doses), pregnancy, breastfeeding.Dosing and dose
1 vaginal tablet a day for 7-10 days. Treatment started 2 – 4 days after menses. The tablet should be introduced deep into the vagina, preferably in the evening before going to bed.
If necessary, may conduct re-treatment.
- itching, burning, pain and irritation in the vagina; thick, white, mucous discharge from the vagina, odorless or with a faint odor, frequent urination; after discontinuation of the drug – the development of vaginal candidiasis.
- burning sensation or irritation of the penis in the sexual partner;
- on the part of the gastrointestinal tract: nausea, change in taste, metallic taste in the mouth, dry mouth, decreased appetite, cramping abdominal pain, nausea, vomiting, constipation or diarrhea;
- Allergic reactions: rash, itching, skin rash;
- headache, dizziness;
- leukopenia or leukocytosis;
- staining of urine red-brown color due to the presence of water-soluble pigment produced in the metabolism of Omnadren 250 results.
In case of any adverse side effects should stop treatment and seek medical advice.Interaction with other drugs
during treatment should avoid alcohol reception (similar disulfiram causes alcohol intolerance).
Caution should be exercised with concomitant administration of some drugs:Warfarin and other indirect anticoagulants. Omnadren 250 results increases the effects of anticoagulants, which leads to increased formation of prothrombin time.
Disulfiram. The development of neurologic symptoms (depression of consciousness, the development of mental disorders), and therefore should not be administered to patients Ginalgin who took disulfiram within the last two weeks.
Cimetidine inhibits metabolism Omnadren 250 results, which may lead to an increase in its concentration in the serum and an increased risk of side effects.
Preparations Li, increases in the plasma concentration of the latter.
Reduction Ginalgina effect under the influence of barbiturates as Omnadren 250 results accelerates inactivation in the liver.
In the period of treatment is recommended to abstain from sexual intercourse.
When specifying a history of changes in the peripheral blood, as well as when using the drug in high doses and / or when long-term use requires monitoring of blood count.
Omnadren 250 results may immobilize Treponema that leads to false positive TPI test (Nelson).
During treatment should avoid the performance of potentially hazardous activities that require attention and fast reactions (driving, etc.)
In 5 tablets in blisters made of aluminum foil and three-layer film consisting of layers. Soft aluminum, PVC and polyamide
According 2 in the blister cardboard pack with instructions for use.
In a dry place at a temperature of 15 to 25 o C. Keep out of the reach of children.